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5-Amino-1MQ (5-amino-1-methylquinolinum) is a small-molecule compound best known for its role in metabolism and fat regulation. It works by blocking an enzyme called NNMT (nicotinamide-N-methyltransferase), which the body uses to store fat and which is often overactive in obesity, metabolic dysfunction, and reduced NAD+ availability. By inhibiting NNMT, 5-Amino-1MQ is widely researched for its potential to raise cellular NAD+ levels, support fat loss, and improve overall metabolic health.

Key information and effects

  • NNMT inhibition: By blocking NNMT, 5-Amino-1MQ may increase cellular NAD+ levels, supporting better energy production and metabolic function.
  • Fat-loss support: Research suggests it can reduce the size of fat cells (adipocytes) and decrease fat accumulation, potentially aiding in weight management.
  • Enhanced energy metabolism: Increased NAD+ availability can improve mitochondrial efficiency and cellular energy output.
  • Muscle preservation: Some early studies indicate weight loss from 5-Amino-1MQ may spare muscle tissue while reducing fat mass.
  • Anti-inflammatory effects: NNMT inhibition may reduce inflammatory signaling associated with obesity and metabolic syndrome.
  • Cognitive and cellular benefits: Higher NAD+ levels are linked to improved cellular repair, mitochondrial health, and potentially enhanced cognitive function.

Disclaimer: This product is for laboratory research purposes only. Not for human or animal consumption. Cap colour subject to change.

Reconstitution

Reconstitution is the laboratory process of dissolving a lyophilized (freeze-dried) research compound in a suitable solvent, most commonly bacteriostatic water, to prepare a solution for research use.

Use our Peptide Reconstitution Calculator to work out the solvent volume and concentration for your research parameters.

For laboratory and research use only. Not for human or animal consumption.

Storage

Lyophilized research peptides are generally most stable when stored frozen (around -20 °C), sealed, and protected from light and humidity. Refer to the Certificate of Analysis and product documentation for any compound-specific handling notes.

Once reconstituted, stability and handling vary by compound. Consult the peer-reviewed literature specific to the material you are working with. Minimise repeated freeze-thaw cycles to preserve sample integrity.

For laboratory and research use only. Not for human or animal consumption.

Purity

>=99%

Testing Method

HPLC-MS

COA

COA available on request

Form

Powder

Size / Strength

50mg

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